I knew the lysosomes and peroxisomes because I had discovered them; I knew the mitochondria because I was interested in them. I knew the membrane system because my friend, George Palade, had worked on that. Christian de Duve Read Quote
The possibility that lysosomes might accidentally become ruptured under certain conditions, and kill or injure their host-cells as a result, was considered right after we got our first clues to the existence of these particles. Christian de Duve Read Quote